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21c Museum Hotel

21c Museum Hotel welcomes two pets of any size for an additional fee of $40 per stay. The 'Asleep in a Cyclone' room is not pet friendly. Both dogs and cats are allowed, and well-behaved pets may be left in the room unattended. There are pet relief areas beside the hotel.
Or, browse all pet friendly hotels in Louisville if you’re still looking.

Room Types
Please Select a Room

    • 2 double beds
    • Up to 4 people
    • Pet fee additional
    • 2 double beds
    • Up to 4 people
    • Pet fee additional
    • 1 king bed
    • Up to 3 people
    • Pet fee additional
    • 1 king bed
    • Up to 3 people
    • Pet fee additional
OUR GUARANTEE: Book a room now! Our canine concierge will make sure you’re assigned a pet-friendly room, so there aren’t any surprises at check-in.


The 21C Museum Hotel is located in the heart of Louisvilles business and arts district. Situated eight miles from the Louisville International Standiford Field Airport this hotel is very close to the city of Louisville. This historic hotel includes a 10 000 square foot contemporary art museum featuring a stunning collection of cutting-edge provocative art. A full fitness center and spa makes it easy to unwind. The Proof on main restaurant and lounge features an extraordinary dining experience with both indoor and outdoor seating. The hotel amenities include a dining room a fitness center dataport a convention center a business center meeting rooms and interior corridors. This is a wheelchair accessible hotel. The hotel also offers non-smoking rooms. All 91 rooms including six suites are elegant and comfortable equipped with modern amenities including 42-inch plasma TV Wi-Fi surroundings luxury bedding appointments and original works of art.

Health & Safety

Safe Stay: 21c Museum Hotel has enhanced cleaning and safety measures in place, and follows the ALLSAFE (Accor Hotels) cleanliness and sanitization policy. Masks and hand sanitizer are provided to guests, and rooms are disinfected between each stay. Social distancing measures are in place, as well as physical barriers between staff and guests. Cashless payment is available. Each room has a 24-hour gap period between stays, and hotel staff are required to wear masks.


  • Television
  • Pet Friendly
  • Fitness Center
  • Internet Available
  • Free WiFi
  • Business Center
  • Meeting Rooms
  • Air Conditioning
  • Restaurant
  • Room Service
  • Breakfast Available
  • Spa Services
  • Parking Available
  • Wheelchair Accessible
  • Dry Cleaning
  • Elevator
  • Non-Smoking Property


BringFido Guest Rating
TripAdvisor Traveler Rating

21c Museum Hotel has received a rating of 4.5 out of 5 bones by 2 canine critics on BringFido and 4.5 out of 5 by 1,897 guests on TripAdvisor.

  • Alexis
    Apr. 4, 2022
    Amazing hotel, service, location

    The entire staff at the 21C hotel was wonderful from start to finish. They always made our dog feel like a movie star coming and going and were extremely friendly and accommodating. I will definitely stay here again.

  • Susan on Mar. 15, 2020
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Book with Confidence

  • This hotel’s pet policy has been confirmed by our editors and your reservations will be backed by our no-hassle .
  • Our Canine Concierge will make sure you’re assigned to a pet friendly room, so there won’t be any unpleasant surprises at check-in.
  • And you’re getting a great low rate too! We never charge a booking fee on top of the special negotiated nightly rate.
21c Museum Hotel