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Best Western Plus Santee Inn

Best Western Plus Santee Inn welcomes two pets up to 30 lbs for an additional fee of $20 per stay. Standard King and Standard Double Queen rooms on the ground floor allow pets. Accessible rooms are not pet friendly There are grassy areas for pet relief on the property.
Or, browse all pet friendly hotels in Santee if you’re still looking.

Room Types
Please Select a Room

    • 1 queen bed
    • Up to 2 people
    • 2 double beds
    • Up to 4 people
    • 2 double beds
    • Up to 4 people
    • 2 double beds
    • Up to 4 people
    • 1 queen bed
    • Up to 2 people
    • 1 queen bed
    • Up to 2 people
    • 2 double beds
    • Up to 4 people
    • 1 queen bed
    • Up to 2 people
OUR GUARANTEE: Book a room now! Our canine concierge will make sure you’re assigned a pet-friendly room, so there aren’t any surprises at check-in.


Conveniently located off I-95, this Santee hotel offers cozy guest rooms and easy access to area attractions, including golf courses and state parks. Rated number one on TripAdvisor for the Town of Santee, the Best Western Plus Santee Inn offers spacious, comfortable and well-appointed guest rooms, each ground-level room complete with parking just outside your door, cable satellite television with HBO and free high-speed Internet access. Other amenities at this Santee State Park hotel also include a complimentary deluxe continental breakfast each morning, an outdoor heated swimming pool and an on-site restaurant for grabbing a quick bite to eat. Traveling on business? The Best Western Plus Santee Inn is the perfect stop to rest and relax while traveling along the East Coast, and we even offer meeting facilities for a more productive stay. While staying in town, be sure to visit local area attractions that surround this hotel in Santee, including Santee State Park, the National Wildlife Refuge, beautiful Lake Marion and more. Plus with many golf courses located just two miles away, like Santee Cooper Golf Resort and National Golf Course, if you are looking to get some time in on the fairways this is the place! When visiting Santee, South Carolina, there's only one place to stay, the Best Western Plus Santee Inn. Make your reservations online today to save at this spectacular hotel with a convenient location along I-95.

Health & Safety

Safe Stay: Best Western Plus Santee Inn has enhanced cleaning and safety measures in place, and follows the We Care Clean (Best Western) cleanliness and sanitization policy. Hand sanitizer is provided to guests, and rooms are disinfected between each stay. Hotel staff are required to wear masks.


  • Television
  • Pet Friendly
  • Swimming Pool
  • Free WiFi
  • Free Breakfast


BringFido Guest Rating
TripAdvisor Traveler Rating

Best Western Plus Santee Inn has received a rating of 4.2 out of 5 bones by 31 canine critics on BringFido and 4.5 out of 5 in 1,237 guests on TripAdvisor.

  • Elizabeth
    Sep. 13, 2021
    Comfy, quiet and lots of grass for pup!

    We realized we had stayed here before and had no issues in the past. This time around, we again had no issues. The only improvement I would make is a squishy pillow and a magic eraser for the walls. That being said. The actual room was astonishingly clean. I mean, behind tv, top of bed frames, all those spots that are often overlooked. The A/C worked great, the room was quiet and comfortable. Will absolutely stay again.

  • Debi
    Sep. 8, 2021
    Santee overnight on way to Florida

    Clean convenient hotel all first floor rooms with parking directly outside your room. Easy access to dog walk area. Nice restaurant next door.

  • Mary
    Sep. 6, 2021
    On our way to Florida

    The room was clean and the breakfast was great! Plenty of green space for the pups. The rooms only offer double beds so with four adult size people and 2 puppies it was a very tight fit. Staff very friendly, would suggest this as a puppy hotel option.

  • Sara
    Sep. 2, 2021
    Great location

    Great location! Right off the freeway, restaurants real close. I stayed in a regular room my parents stayed in a handicap accessible room and they were very pleased!

  • Lauren
    Aug. 26, 2021
    Great place!

    This place is comfortable, clean, and safe. There was a yard where I could walk my dog around and she had a great time!

  • Greg
    Aug. 15, 2021
    Perfect for a one nighter

    Nice location, clean room, perfect for the fur baby.

  • Carolyn
    Aug. 13, 2021
    Great location

    Great place for people and dogs.

  • Erin
    Jul. 29, 2021
    Great service and location

    Perfect place to stay after a long day of driving.

  • Linda
    Jul. 15, 2021
    Good overnight stay with pets

    Room was comfortable, odor free, and clean. Bed was very comfortable.

  • Sharon
    May. 20, 2021
    Good place to stop off Rt 95

    Nice place to bring hour furry friend. Clean room. Friendly staff and nice breakfast.

  • Ira
    May. 11, 2021
    Perfect for travelers on way back from Florida

    Just what we wanted..and parking is right outside the room

  • Margo
    May. 2, 2021
    easy stay

    Easy check in and all rooms ground floor so easy to settle in. Our cat was a little suspicious of the carpet but settled in nicely.

  • Bianca
    Feb. 13, 2021
    Convenient for Dogs!

    we stopped here on the way to Florida so it was a very convenient location. the access to the room was direct from the parking lot and there was a grassy area so it was easy to take our puppy out for potty breaks and to run around. the room was a decent size for the price and had no carpet which we prefer for our pup. nothing fancy but a good place to sleep for the night!

  • Gerri
    Jan. 25, 2021


  • Gustavo
    Jan. 3, 2021
    As expected.

    Clean, convenient. No frills and fair price. Plenty of space outdoor for our dog to do his thing.

  • Deb
    Oct. 19, 2020
    Great Location on trip to Florida

    Comfortable bed and clean room. You park right outside your room and very convenient if you have a dog as the grass is right across from the parking area.

  • Victoria
    Jul. 1, 2020
    Dirty Room, smoke detector beeping in middle of night. Front desk was nice however

  • Alan
    Jun. 12, 2020
    Best Western Plus Santee, SC

    Nice room. Nice location

  • Melinda
    Apr. 4, 2020
    If you are in the area, stay here!

    This was the best hotel room that we have stayed in when traveling with pets! The room and bathroom were spotless. Also updated and quite large with a comfortable bed and a desk and recliner. There is no carpet to worry about. I would definitely recommend staying here and will return the next time we are in the area.

  • Gary
    Mar. 24, 2020
    Perfect stopover

    I needed a place to stay on my drive back to Pennsylvania from Florida. This was the first time I ever stayed at a hotel with my dog. The location and the hotel were perfect. There were several grassy areas right near the room to take out my dog. The room was totally clean and comfortable. I’ll definitely use this again as my stopping point heading north and south.

  • Daverine
    Mar. 2, 2020
    Great location, but that’s all

    We only stayed one night, but that was enough. As we checked in, we were notified that there was a water pressure problem and that the water would be turned off at 9 am. The pet friendly rooms are on the far side of a different building. There seemed to be a slight odor in the room (may have been cleaner, idk). The sheets and blankets were rough.

  • Robin
    Feb. 23, 2020
    Happy Hounds

    The hotel was very nice, the room was very clean and the breakfast was a big surprise (waffle bar, eggs, sausage, yogurt machine, etc.). Was very pleased that the "dog friendly" room was so clean and updated! This is the place that we stay again when we travel to Florida.

  • Deborah
    Feb. 22, 2020
    Best Western Plus Santee Inn

    Very nice hotel with a great area to walk the dogs. Pet fee was $20 a night for each pet but well worth it. Would recommend this hotel for any pet owner.

  • Jane
    Feb. 10, 2020
    Very nice once again

    This is our 2nd stay and once again it was nice and clean and no complaints

  • Bevin
    Jan. 25, 2020
    Great Motel Stop on I-95

    Comfortable, clean rooms. Convenient first floor pet rooms with units open directly to parking area, no going through lobby. Good bar and restaurant right on property. Highly recommended.

  • Karen
    Nov. 1, 2019
    Guest Review

    A perfect stop with our Lab. Though an older facility, it has been nicely updated, is very clean, and staff is very friendly. We love having our own exterior door. And there was a lot of grass for walking..

  • Mike on Jun. 11, 2021
  • Marc on May. 5, 2021
  • Ellen on Dec. 17, 2020
  • Dave on Mar. 7, 2020
  • Linda on Sep. 15, 2019
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Book with Confidence

  • This hotel’s pet policy has been confirmed by our editors and your reservations will be backed by our no-hassle .
  • Our Canine Concierge will make sure you’re assigned to a pet friendly room, so there won’t be any unpleasant surprises at check-in.
  • And you’re getting a great low rate too! We never charge a booking fee on top of the special negotiated nightly rate.
Best Western Plus Santee Inn